VWD occurs in approximately 1% of the population, including more than 3
million people in the US alone. It's primarily a hereditary disease and occurs
in women and men in equal numbers.1
VWD was named after Dr. Erik von Willebrand, who discovered the disease in a 5-year-old Finnish girl in 1924.2 It is a bleeding disorder that makes it difficult to form blood clots, resulting in more frequent bleeds that last longer than normal.1
VWD is usually hereditary, meaning it's passed down from a parent to a child. In some rare instances, a child can have the disease without a family history of VWD.1
VWD can be caused by either3:
All 3 types of VWD may cause severe or frequent bleeds or symptoms.4
VWD symptoms include6:
Tracking your bleeds can help your healthcare provider better understand how VWD is affecting your body. Download our handy bleed tracker to get started today.
Download bleed tracker Descargar registro de sangradosOur easy-to-use Discussion Guide, used alongside our bleed tracker, can help you speak to your healthcare provider about finding a treatment that's right for you.
Download the guideIn most cases, diagnosing VWD involves reviewing your personal history of abnormal bleeding or bruising, along with screening and diagnostic tests. These tests show your healthcare provider the amount of clotting proteins (VWF and FVIII) in your blood and if those proteins are functioning properly or not.7
Even though it's the most common inherited bleeding disorder, many people with VWD face a long road to diagnosis. In one survey of women with VWD, there was an average of 16 years (range 0-39) between the first symptoms and diagnosis of a bleeding disorder.8 As a result, it is suspected that there are many undiagnosed people living with VWD.9 76% of 42 men with VWD had been diagnosed by age 10, but 50% of 38 women with VWD were not diagnosed until after age 12.10 An accurate diagnosis is extremely important for women in order to avoid unnecessary and/or invasive treatments, such as hysterectomy.5
VONVENDI was created specifically to treat bleeding episodes in adults with VWD. When infused into your blood stream, it acts like your body's natural von Willebrand factor (VWF), helping to form clots, and helping your own FVIII to work.5111
VONVENDI is approved for use in adults with VWD Types 1, 2, and 3.612 It can also be prescribed to manage bleeds in three different ways:
What is VONVENDI?
VONVENDI is used in adults (age 18 years and older) diagnosed with von Willebrand disease to:
Who should not use VONVENDI?
You should not use VONVENDI if you: